Publications by authors named "C E Parr"

The 3' untranslated region (3'UTR) plays a crucial role in determining mRNA stability, localisation, translation and degradation. Cap analysis of gene expression (CAGE), a method for the detection of capped 5' ends of mRNAs, additionally reveals a large number of apparently 5' capped RNAs derived from locations within the body of the transcript, including 3'UTRs. Here, we provide direct evidence that these 3'UTR-derived RNAs are indeed capped and widespread in mammalian cells.

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Habitat fragmentation is a major threat to biodiversity, but existing literature largely ignores naturally patchy ecosystems in favor of forests, where deforestation creates spatially distinct fragments. Here, we use savannas to highlight the problems with applying forest fragmentation principles to spatially patchy ecosystems. Identifying fragmentation using landscape functionality, specifically connectivity, enables better understanding of ecosystem dynamics.

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Article Synopsis
  • Low maternal vitamin D levels during pregnancy have been linked to various health issues in offspring and may affect DNA methylation, a process that influences gene expression.
  • The study examined the relationship between maternal vitamin D insufficiency (defined as less than 75 nmol/L) and DNA methylation patterns in the cord blood of newborns using data from 3738 mother-child pairs across seven cohorts.
  • Despite a significant prevalence of vitamin D insufficiency among the mothers (ranging from 44.3% to 78.5%), the research found no significant association between maternal vitamin D levels and DNA methylation at the analyzed sites after adjusting for various factors.
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Scavenging is a key process for the cycling of nutrients in ecosystems, yet it is still neglected in the ecological literature. Apart from the importance of specific groups of animals in scavenging, there have been few ecological studies that compare them. Furthermore, the ecological studies on scavenging have mainly focused on vertebrates despite the crucial importance of invertebrates in this process.

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