Publications by authors named "C E Kossmann"

Background: The participative design of work processes is hampered by as-yet unresolved challenges. A root cause is seen in high information-pass-on-barriers. Virtual Reality (VR) may have a significant potential to overcome these challenges.

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Article Synopsis
  • Advances in chemical protein synthesis now allow for the creation of custom proteins with various modifications, leading to better control over posttranslational modifications (PTMs).
  • Expressed protein ligation (EPL) is utilized to incorporate specific amino acid analogs and mutations in PDZ (postsynaptic density) protein domains, facilitating the study of their protein-protein interactions (PPIs).
  • The text provides protocols for performing EPL on PDZ domains, specifically highlighting modifications related to phosphorylation and amide-to-ester changes.
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Introduction: A disturbed sense of self is frequently discussed as an etiological factor for delusion symptoms in psychosis. Phenomenological approaches to psychopathology posit that lacking the sense that the self is localized within one's bodily boundaries (disembodiment) is one of the core features of the disturbed self in psychosis. The present study examines this idea by experimentally manipulating the sense of bodily boundaries.

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Background: This study addresses the question of whether psychosocial functioning measured by the Personal and Social Performance (PSP) Scale is related to various psychopathological measures in a cohort of patients with schizophrenia.

Methods: The 'Neuroleptic Strategy Study' (NeSSy) performed at 14 German hospitals between 2010 and 2013 compared two treatment strategies instead of individual drugs. Secondary end-points were the two PSP scales as well as measures of quality of life (SF-36) and the Positive and Negative Syndrome Scale (PANSS).

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