Case Report: Buprenorphine for Palliation in a Patient with End Stage Renal Disease.

End stage renal disease (ESRD) is known to be associated with pain, malaise and decreased quality of life. Pain management in the setting of dialysis is particularly challenging from a pharmacologic standpoint given altered pharmacokinetics of pain medications. Buprenorphine, a partial mu opioid receptor agonist, demonstrates superior safety profile compared to full mu opioid receptor agonists.

Effect of the time scale on the uncertainty of geometric mean concentrations of fecal indicators in creek under baseflow conditions.

Geometric mean concentrations of fecal indicator bacteria E. coli and enterococci are commonly used to evaluate the microbial quality of irrigation, recreation, and other types of waters, as well in watershed-scale microbial water quality modeling. It is not known how the uncertainty of those geometric mean concentrations depends on the time period between sampling.

Temporal stability of E. coli and Enterococci concentrations in a Pennsylvania creek.

Microbial quality of irrigation waters is a substantial food safety factor. Escherichia coli (E. coli) and Enterococci are used as the fecal indicator bacteria (FIB) to assess microbial water quality.

'It's nothing you could ever prepare anyone for': the experiences of young people and their families following parental stroke.

Aims: This study sought to explore the experiences of young people (aged 8-16) and their families following parental acquired brain injury (ABI), with the aim of developing an understanding of the ways in which members of a family make sense of events post-injury, and to consider the implications of different perspectives on adjustment and coping.

Design: The study applied a qualitative approach using a thematic analysis methodology.

Procedure: Individual semi-structured interviews were conducted with 10 individuals from three families affected by parental stroke.

Release from Streambed to Water Column during Baseflow Periods: A Modeling Study.

Streambed sediments can harbor large populations that are released into the water column during high-flow events. Few studies have been conducted on the rates of transfer from streambed sediment to water column in low-flow conditions in natural streams. The aim of this work was to apply the watershed-scale model SWAT (Soil and Water Assessment Tool) to a natural stream to evaluate the need to account for the release from streambed sediments during baseflow periods and to compare the results of simulating such a release by assuming predominantly passive transport, driven by groundwater influx, against simulations assuming predominantly active transport of random or chemotaxis-driven bacteria movement.