The emergence of bacterial resistance and the increasing restrictions on the use of agrochemicals are boosting the search for novel, sustainable antibiotics. Antimicrobial peptides (AMPs) arise as a new generation of antibiotics due to their effectiveness at low doses and biocompatibility. We compared the antimicrobial activity of four promising AMPs (CA-M, BP100, RW-BP100, and 3.
View Article and Find Full Text PDFMild cognitive impairment (MCI) refers to cognitive alterations with preservation of functionality. Individuals with this diagnosis have a higher risk of developing dementia. Non-pharmacological interventions, such as physical exercise, are beneficial for the cognition of this population.
View Article and Find Full Text PDFEarly-onset Alzheimer's disease (EOAD) is less investigated than the more common late-onset Alzheimer's disease (LOAD) despite its more aggressive course. A cortical signature of EOAD was recently proposed and may facilitate EOAD investigation. Here, we aimed to validate this proposed MRI biomarker of EOAD neurodegeneration in an Appalachian clinical cohort.
View Article and Find Full Text PDFEstuaries are the main pathway for the microplastics (MPs) to enter into the oceans. However, factors that drive river-sea transport of MPs are not yet fully understood. Therefore, our research investigated the influence of the tidal cycle on the abundance and characteristics of MPs in an urban estuary, through high-frequency sampling (every 2-3 h) using a plankton net (120 μm mesh size) in two seasons (rainy and dry seasons).
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