[Low-dose polyethylene glycol 4000: digestive effects. Randomized double-blind study in healthy subjects].

Objectives: It was recently demonstrated that low-dose polyethylene glycol 4000 (PEG) electrolyte lavage solution, a colonic lavage solution used for cleaning the gut before colonic procedures, is effective in the treatment of chronic constipation. The aim of our study was to determine the digestive effects of low-dose PEG 4000 without electrolyte addition in healthy subjects.

Methods: Sixteen healthy male subjects with normal transit were included in a randomized controlled cross-over study.