Publications by authors named "C Du Boisbaudry"

In paediatrics, the pulmonary function test (PFT) is most often performed to support the diagnosis or in follow-up of asthma patients. Whatever the pathology responsible for respiratory symptoms and/or functional impairment, repeated PFTs make it possible to establish a prognosis (pulmonary function trajectories…) and to orient preventive interventions. PFT can be performed routinely from the age of three years, provided that the following requirements are met: suitable techniques and equipment, staff trained to apply the techniques and to receive young children, reference values for each technique indicating the limits of normal values and of between-test significant variation.

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Article Synopsis
  • The study evaluated airway function in preschool children using two techniques: interrupter resistance (Rint) and specific airway resistance (sRaw), focusing on their baseline measurements and bronchodilator response (BDR).
  • A strong correlation was found between Rint and sRaw measurements, but with poor agreement, indicating that using just one method might not be reliable for diagnosing airway obstruction.
  • Children with worse asthma control showed significantly higher baseline measurements and post-bronchodilator changes, prompting the conclusion that both Rint and sRaw should be conducted together alongside BDR tests for better accuracy.
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Background: Among the different techniques used to monitor lung disease progression in infants with CF diagnosed by Newborn screening (NBS), raised volume-rapid thoracic compression (RVRTC) remains a promising tool. However, the need of sedation and positive pressure ventilation considerably limits its clinical use. We recently described a semi-quantitative method to evaluate air trapping by chest tomography during quite breathing without sedation (CTqb score).

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