New therapeutics are necessary for preventing Plasmodium vivax malaria due to easy transmissibility and dormancy in the liver that increases the clinical burden due to recurrent relapse. In this manuscript we characterize 12 Pv Apical Membrane Antigen 1 (PvAMA1) specific human monoclonal antibodies from Peripheral Blood Mononuclear Cells of a Pv-exposed individual. PvAMA1 is essential for sporozoite and merozoite invasion, making it a unique therapeutic target.
View Article and Find Full Text PDFBackground: Hispanics/Latinos are the largest racial/ethnic group among underrepresented populations in the U.S. and multiple sociodemographic, cultural, and linguistic factors have been found to impact their performances on cognitive testing.
View Article and Find Full Text PDFBackground: Hispanics are a significant demographic in the U.S., with diverse cultures and languages.
View Article and Find Full Text PDFBackground: Normative data for Spanish-speaking populations, particularly Hispanics in the U.S., is notably scarce.
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