Publications by authors named "C Dow"

Cognitive impairment following surgery is a significant complication, affecting multiple neurocognitive domains. The term "perioperative neurocognitive disorders" (PND) is recommended to encompass this entity. Individuals who develop PND are typically older and have increases in serum and brain pro-inflammatory cytokines notwithstanding the type of surgery undergone.

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  • A study investigated how the antioxidant capacity and inflammation potential of maternal diets during the last three months of pregnancy could influence the risk of allergic and respiratory diseases in children.
  • Researchers analyzed data from 9,679 mother-child pairs, measuring the dietary antioxidant capacity and inflammatory potential using various indices.
  • Results indicated that a diet high in antioxidants was linked to a lower risk of 'early wheeze without asthma,' while a pro-inflammatory diet correlated with a higher risk of 'asthma only,' suggesting maternal diet impacts children's respiratory health to some extent.
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Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that, over millions of years, became integrated into the human genome. While normally inactive, environmental stimuli such as infections have contributed to the transcriptional reactivation of HERV-promoting pathological conditions, including the development of autoimmunity, neurodegenerative disease and cancer. What infections trigger HERV activation? subspecies (MAP) is a pluripotent driver of human disease.

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  • The study investigates how maternal diet during pregnancy affects exposure to toxic trace elements like arsenic, mercury, and lead.
  • It found that women with healthier dietary patterns had higher levels of arsenic and mercury in their bodies, while lead levels in cord blood were less directly linked to diet.
  • Interestingly, a Western dietary pattern was connected to lower mercury levels, suggesting that not all "healthy" foods are equal when it comes to toxic exposure during pregnancy.
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Warm water from the Southern Ocean has a dominant impact on the evolution of Antarctic glaciers and in turn on their contribution to sea level rise. Using a continuous time series of daily-repeat satellite synthetic-aperture radar interferometry data from the ICEYE constellation collected in March-June 2023, we document an ice grounding zone, or region of tidally controlled migration of the transition boundary between grounded ice and ice afloat in the ocean, at the main trunk of Thwaites Glacier, West Antarctica, a strong contributor to sea level rise with an ice volume equivalent to a 0.6-m global sea level rise.

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