Publications by authors named "C Djediat"

Article Synopsis
  • - Platelet aggregation in the lungs may contribute to thrombocytopenia during acute pulmonary hypertension (PH) decompensation, as observed in lung transplant patients.
  • - A study involving 16 patients identified a significantly higher number of platelet aggregates in those experiencing thrombocytopenia compared to control patients without PH.
  • - Scanning electron microscopy revealed that the capillaries in the lungs of patients with acute PH decompensation were filled with these platelet aggregates, indicating a potential mechanism for the condition.
View Article and Find Full Text PDF
Article Synopsis
  • Bone is formed by osteoblasts releasing a substance called osteoid, which eventually undergoes mineralization and creates an organized texture, known as plywood geometry, in trabecular and cortical bones.
  • This study uses sheep, a common model in orthopedic research, to show that the deeper layer of osteoid is structured in a unique liquid-crystal configuration influenced by its acidic environment, promoting collagen arrangement.
  • Findings indicate that the collagen structures in bone develop gradually through natural processes, suggesting that understanding these collagen patterns could help in studying bone diseases arising from irregularities in the collagen maturation process.
View Article and Find Full Text PDF

Cyanobacterial blooms can modify the dynamic of aquatic ecosystems and have harmful consequences for human activities. Moreover, cyanobacteria can produce a variety of cyanotoxins, including microcystins, but little is known about the role of environmental factors on the prevalence of microcystin producers in the cyanobacterial bloom dynamics. This study aimed to better understand the success of Planktothrix in various environments by unveiling the variety of strategies governing cell responses to sudden changes in light intensity and temperature.

View Article and Find Full Text PDF

Background: The pathophysiology of AKI during tumor lysis syndrome (TLS) is not well understood due to the paucity of data. We aimed to decipher crystal-dependent and crystal-independent mechanisms of TLS-induced AKI.

Methods: Crystalluria, plasma cytokine levels, and extracellular histones levels were measured in two cohorts of patients with TLS.

View Article and Find Full Text PDF

The presence of phosphate from different origins (inorganic, bioorganic) is found more and more in calcium carbonate-based biominerals. Phosphate is often described as being responsible for the stabilization of the transient amorphous calcium carbonate phase. In order to specify the composition of the mineral phase deposited at the onset of carbonated shell formation, the present study investigates, down to the nanoscale, the growing shell from the European abalone Haliotis tuberculata, using a combination of solid state nuclear magnetic resonance, scanning transmission electron microscope and spatially-resolved electron energy loss spectroscopy techniques.

View Article and Find Full Text PDF