Monoclonal Antibodies Targeting CGRP: A Novel Treatment in Vestibular Migraine.

. Monoclonal antibodies (mAbs) directed against the calcitonin gene-related peptide (CGRP) or its receptor represented the first targeted and specialized approach to migraine prophylaxis. Nevertheless, they have been rarely considered in the treatment of vestibular migraine (VM).

Ratio Aβ1-42:p-Tau: a Possible Diagnostic Tool in Differentiating Dementias.

Background: Patients with Alzheimer's disease (AD) present a typical biochemical profile of biomarkers: low concentration of β amyloid 1-42 (Aβ1-42), high concentration of total Tau (t-Tau) and phosphorylated Tau at threonine 181 (p-Tau). Several neurodegenerative diseases may overlap with AD, both in regards to clinical symptoms and neuropathology. Many data suggest that Alzheimer's disease (AD) pathophysiology can be identified using biomarkers.

Angiotensin II receptor blockers: a new possible treatment for chronic migraine?

The objective is to suggest a possible role of different angiotensin receptor blockers in the treatment of chronic migraine, especially in hypertensive subjects. Chronic migraine is a highly disabling disorder affecting between 1.4 and 2.