Antimicrobial, anti-cancer, anti-filarial and anti-inflammatory activities of Cowabenzophenone A extracted from the endophytic fungus isolated from a mangrove plant .

Cowabenzophenone A was isolated from an endophytic fungus Aspergillus terreus isolated from a mangrove plant Bruguiera gymnorrhyza. The structure was determined by analysis of 1D and 2D NMR spectra and mass spectrometric data as a tetracyclo[7.3.

Antimicrobial activities of endophytic fungi of the Sri Lankan aquatic plant and chaetoglobosin A and C, produced by the endophytic fungus .

Twenty distinct endophytic fungi were isolated from the surface-sterilized plant parts of and were identified using morphological and molecular techniques. At 300 µg/disc concentration, eight of the 20 fungal extracts exhibited antimicrobial activities against (ATCC 25923) and (ATCC 11778) while two within the eight showed activity against (ATCC 9027) and (ATCC 35218). Furthermore, investigation of the crude extract of resulted in the isolation of two known cytochalasans, chaetoglobosin A and C, and their structures were elucidated and confirmed by mass and nuclear magnetic resonance (NMR) (H, C, COSY, HSQC, HMBC and tROESY) spectral data.