Publications by authors named "C DiGuisto"
[Prostaglandins or cervical balloon for the induction of labor for cervical ripening: A literature review].
Gynecol Obstet Fertil Senol
November 2024
Objective: Induction of labor in France concerns one birth out of four with 70% of induction starting by cervical ripening, either with a pharmacological (prostaglandins) or a mechanical (balloon) method. This review aims to compare these two methods within current knowledge, using the PRISMA methodology.
Methods: Trials comparing these two methods, published or unpublished up to July 2023, in French or English were searched for in the PubMed, Cochrane Library and ClinicalTrial.
Article Synopsis
- Pregnant women with fibrinogen levels below 2 g/L are at high risk for severe postpartum hemorrhage and related complications, yet the criteria for identifying those needing fibrinogen therapy are unclear.
- A UK study identified 124 cases of low fibrinogen in pregnant women, mainly linked to postpartum hemorrhage from events like placental abruption or trauma, with a low incidence of inherited conditions.
- The study found high maternal and perinatal mortality rates, including 27 stillbirths and two maternal deaths due to massive hemorrhage, indicating the seriousness of low fibrinogen levels in this population.*
Article Synopsis
- The study aimed to compare the cesarean rates and maternal and neonatal complications among obese pregnant women who needed cervical ripening for labor induction at or after 41 weeks gestation.
- The analysis involved 336 overweight women and examined the effectiveness of various cervical ripening methods: PGE2 pessary, low-dose vaginal PGE1, and double-balloon catheter.
- Results showed no significant difference in cesarean rates between methods, but the PGE2 pessary was associated with fewer perineal tears compared to PGE1, indicating a need for further research on the best methods for this group.
Objective: To develop and validate a clinical prediction model for outcomes at 5 years of age for children born extremely preterm and receiving active perinatal management.
Design: The EPIPAGE-2 national prospective cohort.
Setting: France, 2011.
Aim: To describe the circumstances, causes and timing of death in extremely preterm infants.
Methods: We included from the EPIPAGE-2 study infants born at 24-26 weeks in 2011 admitted to neonatal intensive care units (NICU). Vital status and circumstances of death were used to define three groups of infants: alive at discharge, death with or without withholding or withdrawing life-sustaining treatment (WWLST).