Effects of vegetation on methylmercury concentrations and loads in a mercury contaminated floodplain.

The Yolo Bypass (YB) is a large flood conveyance system designed to protect the city of Sacramento, California, USA from flooding when the Sacramento River approaches flood stage. The Sacramento River watershed and YB are a source of methylmercury (MeHg) to downstream habitat as a result of historic mercury (Hg) and gold mining practices. In the dry season, the YB is extensively farmed and grazed.

Wound Healing After Fractional Skin Harvesting.

Background: Autologous fractional full-thickness skin grafting is a method of harvesting full-thickness skin with reduced donor site morbidity compared with conventional skin grafting.

Objective: To demonstrate that full-thickness skin microbiopsies can be harvested with minimal scarring or complications.

Materials And Methods: In a nonrandomized, self-controlled, pilot trial, subjects ( n = 8) underwent tissue harvesting of full-thickness skin columns of 200, 400, 500, 600, 800 μm, 1, and 2 mm diameters.

Blue light induces DNA damage in normal human skin keratinocytes.

Background: The generation of DNA damage by ultra-violet radiations (UV) is well established, and both the nature of the DNA lesions and their respective DNA repair pathways have largely been described. Besides UV rays, visible light constitutes a very important part of the sun spectrum where blue light is considered a significant contributor to premature aging. However, blue light-induced DNA damage has not been deeply explored yet.

Synthesis, docking and evaluation of in vitro anti-inflammatory activity of novel morpholine capped β-lactam derivatives.

This study reports the synthesis and biological investigation of three series of novel monocyclic β-lactam derivatives bearing a morpholine ring substituent on the nitrogen. The resulting β-lactam adducts were synthesized via Staudinger's [2 + 2]-ketene-imine cycloaddition reaction. New synthesized products were fully characterized by spectral data and elemental analyses, and then evaluated for anti-inflammatory activity toward human inducible nitric oxide synthase (iNOS) and cytotoxicity toward HepG2 cell line.