Publications by authors named "C Deschaumes"
Objectives: Alhough typically prescribed in oncology, bisphosphonates (BPs) are also employed in rheumatology, particularly for the treatment of osteoporosis, sometimes resulting in complications, such as osteonecrosis of the jaw. Because of different opinions between rheumatologists and dentists on BP use, this study aimed to assess the views of dentists regarding administration of BPs in rheumatology.
Methods: A questionnaire was sent to 880 dentists from the Auvergne region of France to determine their views on BP treatment.
Efficacy and safety of a new oral saliva equivalent in the management of xerostomia: a national, multicenter, randomized study.
Oral Surg Oral Med Oral Pathol Oral Radiol
March 2015
Objective And Study Design: The clinical efficacy, safety, and acceptability of a new oral saliva equivalent (Novasial) administered four times daily in the treatment of xerostomia in various medical conditions was compared with that of oxygenated glycerol triester oral spray (Aequasyal) and a moisturizing spray (Biotene) in a 2-week, multicenter, randomized, crossover study. Assessment included patient-based evaluation of mouth dryness score (primary endpoint) with a visual analog scale (VAS), blinded assessment of the oral tissue condition by a four-point ordinal scale, and patient-based assessment of tolerability and acceptability.
Results: At day 14, Novasial decreased oral mouth dryness by 19.
Objectives: This prospective study examined the relationship between resting blood pressure (BP; primary outcome), demographic features of patients, anatomical characteristics of the extracted teeth, surgery variables (secondary outcomes), and acute postsurgical pain in patients undergoing tooth extraction.
Materials And Methods: Standardized surgery was performed under local anesthesia. A composite numerical index, referred to as "postoperative pain/analgesia score" (PPAS), was built out of two intermediate ones, indicating (i) the degree of spontaneous pain reported by the patient (postoperative pain score) and (ii) the amount of analgesic drug intake (postoperative analgesia score).
Article Synopsis
- Erosive degenerative disc disease, or Modic type 1 changes, leads to low back pain resembling inflammatory pain patterns, and pamidronate has shown effectiveness in other painful bone conditions.
- This study, called PEPTIDE, aims to test the efficacy of pamidronate in treating low back pain associated with these changes, involving 48 patients split into two groups receiving either pamidronate or a placebo.
- The primary goal is to see a 30-point improvement on the Visual Analogue Scale for pain at three months, with additional assessments on functionality and safety, while maintaining the blinding of participants through a common pain reliever.