Publications by authors named "C Depuydt"
[CFTR gene variant screening in gamete donation candidates in France: Which indications? How to screen? Why?].
Gynecol Obstet Fertil Senol
January 2025
Objectives: According to French recommendations, only the caryotype is carried out as a first line in candidates for gamete donation. The prescription of additional genetic tests for variants responsible for serious monogenic diseases is only recommended in the case of call points. However, cystic fibrosis remains the most common genetic disease with serious consequences in childhood.
View Article and Find Full Text PDFWe describe a 71-year-old woman who developed interstitial pneumonia within a complex somatic state. Diagnostic clearance suggested venlafaxine-induced interstitial pneumonia. In the literature, we found 13 cases of venlafaxine-induced interstitial pneumonia.
View Article and Find Full Text PDFPurpose: Maintaining a stable pH at optimal level in human embryo culture media is crucial for embryo development but poses a challenge for all IVF laboratories. We validate analytically reliable conditions for pH measurement that are as close as possible to the embryo microenvironment during IVF.
Methods: This was a multicentric study.
Article Synopsis
- The study investigates the short- and long-term impacts of SARS-CoV-2 on sperm quality, revealing a lack of established knowledge due to insufficient longitudinal research.
- Evaluating sperm parameters included assessments like motility, morphology, DNA damage, and the presence of anti-sperm antibodies, which classified patients based on their antibody response post-infection.
- Findings indicate that SARS-CoV-2 affects various sperm quality metrics, with most changes being temporal and suggesting that individual immune response levels influence recovery to baseline sperm quality after infection.
Background: Despite the widespread use of proton density fat fraction (PDFF) measurements with magnetic resonance imaging (MRI) to track disease progression in muscle disorders, it is still unclear how these findings relate to histopathological changes in muscle biopsies of patients with limb-girdle muscular dystrophy autosomal recessive type 12 (LGMDR12). Furthermore, although it is known that LGMDR12 leads to a selective muscle involvement distinct from other muscular dystrophies, the spatial distribution of fat replacement within these muscles is unknown.
Methods: We included 27 adult patients with LGMDR12 and 27 age-matched and sex-matched healthy controls and acquired 6-point Dixon images of the thighs and T1 and short tau inversion recovery (STIR) MR images of the whole body.