Publications by authors named "C Denoyelle"
Article Synopsis
- Ovarian cancer, a leading cause of gynecological cancer deaths, often becomes resistant to chemotherapy, highlighting the urgency for new treatment approaches and predictive biomarkers.
- The OVAREX study investigates the feasibility of creating patient-derived tumor models (like PDX, PDTO, and ADS) to predict clinical outcomes for ovarian cancer patients undergoing treatment.
- This research aims to validate the predictive capabilities of these models by comparing their responses to treatments with actual patient outcomes, potentially enhancing clinical decision-making.
Meat dry aging consists in storing unpackaged meat in a cold room, and at a specific and controlled relative humidity (RH), for a period of 1 to 5 weeks or more. This practice has become widespread in recent years due to its positive effect on the tenderness of the meat but also on other organoleptic characteristics and therefore its market value. The objective of this work was to study the bacterial and fungal microbiota of dry-aged beef at the commercial stage by both culture-dependent and -independent approaches.
View Article and Find Full Text PDFCAR-T cells are T cells expressing a chimeric antigen receptor (CAR) rendering them capable of killing tumor cells after recognition of a target antigen. CD19 CAR-T cells have revolutionized the treatment of hematological malignancies. Their function is typically assessed by cytotoxicity assays using human allogeneic cell lines expressing the target antigen CD19 such as Nalm-6.
View Article and Find Full Text PDFsp. is currently reported as the most frequent single-celled eukaryote inhabiting the intestinal tract of humans and a wide range of animal groups. Its prevalence is especially higher in developing countries linked with fecal peril.
View Article and Find Full Text PDFEpithelial ovarian cancers (EOCs) are a heterogeneous collection of malignancies, each with their own developmental origin, clinical behavior and molecular profile. With less than 5% of EOC cases, mucinous ovarian carcinoma is a rare form with a poor prognosis and a 5-year survival of 11% for advanced stages (III/IV). At the early stages, these malignant forms are clinically difficult to distinguish from borderline (15%) and benign (80%) forms with a better prognosis due to the large size and heterogeneity of mucinous tumors.
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