Publications by authors named "C Demonceau"
The objective of this systematic review and meta-analysis is to assess the carcinogenic effects of extremely low frequency magnetic fields (ELF-MF) by analyzing animal and comet assay studies. We have performed a global meta-analysis on all the animal studies on the relation between ELF-MF and cancer incidence and separate meta-analyses on the incidence of cancer, leukemia, lymphoma, breast cancer, brain cancer and DNA damage assessed with the comet assay. Of the 5145 references identified, 71 studies have been included in our systematic review and 22 studies in our meta-analyses.
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- The study investigates the vitamin D metabolite ratio (VMR) as a potential better indicator of vitamin D deficiency compared to 25-hydroxyvitamin D (25(OH)D) and 24,25-dihydroxyvitamin D (24,25(OH)D), aiming to show its stronger correlation with parathyroid hormone (PTH) levels and mortality.
- It analyzed serum samples from 204 older adults, demonstrating that VMR had the strongest negative correlation with PTH levels and was associated with higher mortality rates in patients with low levels.
- The results suggest that VMR could be a more reliable biomarker for assessing functional vitamin D deficiency, supporting its potential use in clinical practice.
Objectives: The global increase in the older population, which is expected to reach 1.5 billion by 2050, poses significant challenges for publicly funded health care systems. Life expectancy, although positive, is leading to an increase in chronic diseases requiring complex and costly health and social solutions.
View Article and Find Full Text PDFContent validity of SarQoL, a quality of life questionnaire specific to sarcopenia.
Aging Clin Exp Res
April 2024
Background: The Sarcopenia & Quality of Life (SarQoL) questionnaire is a patient-reported outcome measure designed for assessing health-related quality of life in individuals with sarcopenia. Despite its wide acceptance in the scientific literature, its content validity has only been partially demonstrated so far.
Aims: To enhance the evidence supporting the content validity of the SarQoL questionnaire.
Objective: To identify a microRNA signature associated to sarcopenia in community-dwelling older adults form the SarcoPhAge cohort.
Methods: In a screening phase by next generation sequencing (NGS), we compared the hsa-miRome expression of 18 subjects with sarcopenia (79.6 ± 6.