Publications by authors named "C Dejaco"
Reliability of the OMERACT Giant cell arteritis Ultrasonography Score (OGUS): results of a patient-based exercise involving experts and non-experts in vascular ultrasonography.
RMD Open
January 2025
Objective: To test the reliability of the Outcome Measures in Rheumatology Giant cell arteritis (GCA) Ultrasonography Score (OGUS) and other composite scores in a patient-based exercise involving experts and non-experts in vascular ultrasonography.
Methods: Six GCA patients were scanned twice (two rounds separated ≥3 hours) by 12 experts and 12 non-experts. Non-experts received 90 min of theoretical and 240 min of practical training between rounds 1 and 2.
Objective: Polymyalgia rheumatica (PMR) is an inflammatory disorder of the elderly characterized by girdle pain and stiffness. Obesity has an influence on disease activity and outcome in rheumatic diseases like osteoarthritis and rheumatoid arthritis. We aimed to investigate the relationship between high BMI and the severity and outcome of PMR, which is incompletely understood.
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- This case series evaluates the effectiveness and safety of baricitinib (BARI) in treating six patients suffering from polymyalgia rheumatica (PMR) and giant cell arteritis (GCA), particularly when traditional treatments like tocilizumab were unavailable.
- Patients showed significant improvement in symptoms, with a notable reduction in their disease activity scores and the ability of some to discontinue glucocorticoids while on BARI.
- Overall, the findings align with previous studies indicating that Janus kinase inhibitors may serve as a helpful alternative for managing PMR and GCA by reducing reliance on glucocorticoids, although one patient did experience pneumonia after treatment.