Publications by authors named "C DeFilippo"

Cross-pinning of displaced pediatric supracondylar elbow fractures offers a superior stability construct. However, there is a reluctance to use this construct by closed means because of the risk of iatrogenic ulnar nerve injuries associated with percutaneous medial pin placement. This study describes a safe technique for closed reduction percutaneous with medial pin placement.

View Article and Find Full Text PDF

Introduction: Social media utilization is expanding within graduate medical education and academic surgery. This study aims to quantify the current social media footprint of pediatric surgery (PS) fellowship training programs.

Methods: United States PS fellowship programs from the American Pediatric Surgical Association website and social media accounts on three platforms (Facebook, Instagram, Twitter) were identified.

View Article and Find Full Text PDF

Moebius syndrome is a congenital cranial dysinnervation disorder (CCDD) that presents with nonprogressive cranial nerve (CN) VI and VII palsies resulting in facial weakness and inability to abduct the eye(s). While many CCDDs have an underlying genetic cause, the etiology of Moebius syndrome remains unclear as most cases are sporadic. Here, we describe a pair of monochorionic, diamniotic twin girls; one with normal growth and development, and one with micrognathia, reduced facial expression, and poor feeding.

View Article and Find Full Text PDF

is a Gram-positive anaerobic found in soil that is a rare cause of inflammatory infections of the GI tract. This bacterium has a propensity for causing gastritis in patients with delayed gastric emptying. Of the 66 reported cases in the literature, 10 involved the esophagus.

View Article and Find Full Text PDF
Article Synopsis
  • Semaphorins and plexins, important for brain development, include the PLXNA3 gene, which affects brain signaling and is linked to conditions like autism and intellectual disabilities in boys with specific genetic variants.
  • This study examined 14 boys with these hemizygous PLXNA3 variants, finding a range of issues such as autism, motor difficulties, and seizures, highlighting a connection between the gene variations and the severity of neurodevelopmental disorders.
  • The findings suggest a potential new X-linked intellectual disability syndrome tied to PLXNA3 variants and emphasize the need for more research on their impact in humans.
View Article and Find Full Text PDF