Finding polarized communities and tracking information diffusion on Twitter: a network approach on the Irish Abortion Referendum.

The analysis of social networks enables the understanding of social interactions, polarization of ideas and the spread of information, and therefore plays an important role in society. We use Twitter data-as it is a popular venue for the expression of opinion and dissemination of information-to identify opposing sides of a debate and, importantly, to observe how information spreads between these groups in our current polarized climate. To achieve this, we collected over 688 000 tweets from the Irish Abortion Referendum of 2018 to build a conversation network from users' mentions with sentiment-based homophily.

Current evidence on powered versus manual circular staplers in colorectal surgery: a systematic review and meta-analysis.

Purpose: This meta-analysis aims to evaluate the efficacy of powered circular staplers (PCS) compared to manual circular staplers (MCS) in reducing anastomotic leakage (AL) and postoperative bleeding (AB) in colorectal surgery.

Methods: Extensive searches were performed in the Embase, PubMed, and SCOPUS electronic bibliographic databases. Most studies were of an observational nature, and only one randomized clinical trial was identified.

Machine Perfusion for Recovery of Brain Death Donor Hearts from Extended Distances.

The emerging ex vivo machine perfusion (MP) enables the extension of ex situ intervals, potentially expanding the heart transplant (OHT) donor pool. From October 18, 2018, to June 30, 2023, isolated OHT using donation after brain death (DBD) from extended distances (>500 miles) were identified in the United Network for Organ Sharing database, and categorized into cold storage (non-MP, N = 1,212) and MP group (N = 152). The MP utilization rate for DBD hearts from extended distances surged from 0% in 2018 to 27.

Salt Sensitivity of Blood Pressure and the Role of the Immune System in Hypertension.

Salt-sensitive blood pressure is a clinical phenotype defined as exaggerated blood pressure responses to salt loading and salt depletion. This characteristic occurs in 25% of the general population and 50% of patients with hypertension and contributes to the pathogenesis of hypertension in some patients. Hypertension is associated with chronic inflammatory responses and has immune cell accumulation in several hypertensive target organs, including the brain, kidneys, heart, blood vessels, and the perivascular adipose tissue, and these cellular responses likely exacerbate hypertension.

Data-driven analysis identifies novel modulation of social behavior in female mice witnessing chronic social defeat stress.

Background: Chronic social defeat stress is a widely used depression model in male mice. Several proposed adaptations extend this model to females with variable, often marginal effects. We examine if the widely used male-defined metrics of stress are suboptimal in females witnessing defeat.