Publications by authors named "C De Geyter"
Introduction: Chronic low-grade inflammation might contribute to hyperandrogenemia and metabolic complications in polycystic ovary syndrome (PCOS). The proinflammatory cytokine interleukin (IL)-1 stimulates androgen production from ovarian cells, whereas blockade of the IL-1 pathway improves cardiometabolic health. We aimed to investigate whether blocking the IL-1 pathway ameliorates hyperandrogenemia in patients with PCOS.
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- The study investigated the current medically assisted reproduction (MAR) data collection systems across EU Member States and explored how they could contribute to a unified registry for the EuMAR project.
- Significant variations were found in data types, collection methods, and reporting requirements, indicating a need for standardized practices to improve MAR data collection across the EU.
- The cross-sectional study surveyed and interviewed participants from 26 EU countries, revealing that half have national MAR registries with cycle-by-cycle data, while others rely on aggregated data or have no registry at all.
Survey on ART and IUI: legislation, regulation, funding, and registries in European countries-an update.
Hum Reprod
September 2024
Study Question: How are ART and IUI regulated, funded, and registered in European countries, and how has the situation changed since 2018?
Summary Answer: Of the 43 countries performing ART and IUI in Europe, and participating in the survey, specific legislation exists in only 39 countries, public funding varies across and sometimes within countries (and is lacking or minimal in four countries), and national registries are in place in 33 countries; only a small number of changes were identified, most of them in the direction of improving accessibility, through increased public financial support and/or opening access to additional subgroups.
What Is Known Already: The annual reports of the European IVF-Monitoring Consortium (EIM) clearly show the existence of different approaches across Europe regarding accessibility to and efficacy of ART and IUI treatments. In a previous survey, some coherent information was gathered about how those techniques were regulated, funded, and registered in European countries, showing that diversity is the paradigm in this medical field.
Study Question: Which clinical and embryological factors should be considered to apply double embryo transfer (DET) instead of elective single embryo transfer (eSET)?
Summary Answer: No clinical or embryological factor per se justifies a recommendation of DET instead of eSET in IVF/ICSI.
What Is Known Already: DET is correlated with a higher rate of multiple pregnancy, leading to a subsequent increase in complications for both mother and babies. These complications include preterm birth, low birthweight, and other perinatal adverse outcomes.
Article Synopsis
- Family-planning policies traditionally focused on contraceptives to control population growth, but many countries now experience fertility rates below replacement level, leading to predicted population declines by 2100.
- In response to these declining population trends, countries are exploring child-friendly policies, including financial incentives and limited funding for fertility treatments, to encourage family growth.
- The IFFS consensus document highlights disparities in access to fertility care and emphasizes the need for a broader understanding of family building, encompassing various methods like natural conception, ART, surrogacy, and adoption.