Publications by authors named "C De Deyne"
Background: We aimed to study the incidence of acute kidney injury (AKI) in out-of-hospital cardiac arrest (OHCA) patients treated according to low-normal or high-normal mean arterial pressure (MAP) targets.
Methods: A post hoc analysis of the COMACARE (NCT02698917) and Neuroprotect (NCT02541591) trials that randomized patients to lower or higher targets for the first 36 h of intensive care. Kidney function was defined using the Kidney Disease Improving Global Outcome (KDIGO) classification.
Purpose: Fluid boluses (FB) are often used in post-cardiac arrest (CA) patients with haemodynamic instability. Although FB may improve cardiac output (CO) and mean arterial pressure (MAP), FB may also increase central venous pressure (CVP), reduce arterial PaO, dilute haemoglobin and cause interstitial oedema. The aim of the present study was to investigate the net effect of FB administration on cerebral tissue oxygenation saturation (SctO) in post-CA patients.
View Article and Find Full Text PDFBackground: In patients with shock after acute myocardial infarction (AMI), the optimal level of pharmacologic support is unknown. Whereas higher doses may increase myocardial oxygen consumption and induce arrhythmias, diastolic hypotension may reduce coronary perfusion and increase infarct size.
Objectives: This study aimed to determine the optimal mean arterial pressure (MAP) in patients with AMI and shock after cardiac arrest.
We aimed to confirm the positive association between a successful electrical cardioversion (ECV) and increase in SctO and investigated whether this increase is persisting or not. Secondary, the influence of a successful ECV on the neuropsychological function and the association with SctO was assessed as well. SctO was measured continuously during elective ECV using near-infrared spectroscopy.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated the link between cerebral oxygen levels and postoperative delirium in older cardiac surgery patients, finding that while intraoperative oxygen levels weren't significantly tied to delirium, lower postoperative oxygen levels were associated with increased delirium rates.
- Of the 103 patients studied, about 30% experienced delirium, with particularly noticeable drops in oxygen levels among those affected.
- Factors like older age, prior strokes, and certain pre-existing health assessments were independently linked to higher incidences of delirium post-surgery.