Background: Type 1 interferon (IFN-I) response induced by SARS-CoV-2 has been hypothesized to explain the association between chilblain lesions (CL) and SARS-CoV-2 infection.
Objective: To explore direct cytopathogenicity of SARS-CoV-2 in CL and to focus on IFN-I expression in patients with chilblains.
Materials & Methods: A monocentric cohort of 43 patients presenting with CL from April 2020 to May 2021 were included.
Importance: During the coronavirus disease 2019 (COVID-19) pandemic, several cases of chilblains have been reported.
Objective: To determine if chilblains are associated with COVID-19.
Design, Setting, And Participants: This monocentric case series was conducted at the Department of Dermatology at Cliniques universitaires Saint-Luc, a tertiary care hospital in Brussels, Belgium, between April 10 and April 17, 2020.
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma, characterized by systemic symptoms, diffuse lymphadenopathy, hepatosplenomegaly and immunodysregulation. Half of AITL is associated with cutaneous symptoms, but only few cases with bullous eruption have been described. Association with a linear IgA dermatosis is extremely rare.
View Article and Find Full Text PDFBackground: CD8+ CD30+ primary cutaneous T-cell lymphomas (PCTCL) are rare entities with overlapping pathological features and variable outcome.
Objectives: We sought to highlight the importance of correlation between pathological findings and clinical presentation for correct classification of the disease.
Materials & Methods: Two cases of CD8+ CD30+ PCTCL were investigated.