Publications by authors named "C D. Shriver"

Background: Pancreatic cancer has a high case fatality and treatment is known to improve survival. It is unknown whether the time between diagnosis and treatment initiation (time-to-treatment) is related to survival. Access to medical care may influence both treatment receipt and timing.

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Solid tumors vary by the immunogenic potential of the tumor microenvironment (TME) and the likelihood of response to immunotherapy. The emerging literature has identified key immune cell populations that significantly impact immune activation or suppression within the TME. This study investigated candidate T-cell populations and their differential infiltration within different tumor types as estimated from mRNA co-expression levels of the corresponding cellular markers.

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Background: Soft tissue sarcoma (STS) is one of the most frequently diagnosed cancers among men younger than age 30 years and a leading cause of cancer death in men younger than age 40 years. The military may be more exposed to STS risk factors and have generally better health and health care access than the general population, which may relate to lower cancer risk and/or early detection. This study compared STS incidence between servicemen and men in the general U.

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Article Synopsis
  • This study investigated the link between statin use and survival rates in head and neck cancer patients within the U.S. military health system, aiming to determine if post-diagnosis statin use improves overall survival.
  • It analyzed data from 1,842 patients using time-dependent models, finding that increased statin use after diagnosis significantly enhanced survival, with an adjusted hazard ratio of 0.70 for cumulative use.
  • Results indicated that patients who used statins before and after diagnosis had even better survival rates (HR 0.31), while those who started only after diagnosis had a lesser impact (HR 0.81).
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