Publications by authors named "C D Short"
Background: There are no approved oral disease-modifying treatments for Alzheimer's disease (AD).
Objectives: The objective of this study was to assess efficacy and safety of blarcamesine (ANAVEX®2-73), an orally available small-molecule activator of the sigma-1 receptor (SIGMAR1) in early AD through restoration of cellular homeostasis including autophagy enhancement.
Design: ANAVEX2-73-AD-004 was a randomized, double-blind, placebo-controlled, 48-week Phase IIb/III trial.
There is a risk of re-traumatisation for survivors of trauma who engage with the Justice system, given their high propensity to encounter situations that trigger traumatic responses. While a growing body of research has explored the experience of trauma informed practice (TIP) from service user perspectives, little research has incorporated the views and experiences of practitioners working in the Justice system in terms of the implementation of TIP in their service setting. An exploratory, qualitative research design based on semi-structured, in-depth interviews.
View Article and Find Full Text PDFBackground: Strong evidence supports the benefits of exercise following both cardiovascular disease and cancer diagnoses. However, less than one-third of Australians who are referred to exercise rehabilitation complete a program following a cardiac diagnosis. Technological advances make it increasingly possible to embed real-time supervision, tailored exercise prescription, behavior change, and social support into home-based programs.
View Article and Find Full Text PDFArticle Synopsis
- Frontal alpha asymmetry was thought to indicate levels of approach motivation, but recent studies found little connection between it and personality traits.
- A study using data from the CoScience project (n=740) measured frontal asymmetry during different tasks to see if it varied based on approach motivation.
- The results showed that frontal asymmetry wasn't significantly influenced by the tasks and did not correlate with self-reported personality traits, undermining its validity as a marker for approach motivation.
Article Synopsis
- Overdose fatality review teams (OFRTs) are increasingly utilized in U.S. communities to combat the overdose epidemic, yet there is a lack of research on their effectiveness.
- In a study analyzing recommendations from 19 county-level OFRTs in Indiana during 2022, a total of 1512 recommendations were made, with a significant portion targeting broader community issues rather than specific cases.
- The findings emphasize the need for improved overdose prevention strategies, greater support for OFRTs, and further research to enhance their impact.