Comparative Analysis of Polyethylene-Oxidizing Laccases: Redox Properties and Enzyme-Polyethylene Interaction Mechanism.

Laccases that oxidize low-density polyethylene (LDPE) represent a promising strategy for bioremediation purposes. To rationalize or optimize their PE-oxidative activity, two fundamental factors must be considered: the enzyme's redox potential and its binding affinity/mode towards LDPE. Indeed, a stable laccase-PE complex may facilitate a thermodynamically unfavorable electron transfer, even without redox mediators.

Structural insights into temperature-dependent dynamics of METPsc1, a miniaturized electron-transfer protein.

The design of protein-metal complexes is rapidly advancing, with applications spanning catalysis, sensing, and bioremediation. We report a comprehensive investigation of METPsc1, a Miniaturized Electron Transfer Protein, in complex with cadmium. This study elucidates the impact of metal coordination on protein folding and structural dynamics across temperatures from 100 K to 300 K.

Spatiotemporal modeling of the potential impact of climate change on shifts in bioclimatic zones in Morocco.

This study aims to contribute to the understanding of the impact of climate change on bioclimatic zones in Morocco, providing insights into potential shifts and emphasizing the need for adaptation measures to protect vulnerable species and ecosystems. To achieve this, we utilized eight general circulation models (GCMs) to simulate climate conditions under two representative concentration scenarios (RCP4.5 and RCP8.

On the dual role of (+)-catechin as primary antioxidant and inhibitor of viral proteases.

Natural antioxidants have become the subject of many investigations due to the role that they play in the reduction of oxidative stress. Their main scavenging mechanisms concern the direct inactivation of free radicals and the coordination of metal ions involved in Fenton-like reactions. Recently, increasing attention has been paid to non-covalent inhibition of enzymes involved in different diseases by the antioxidants.