Publications by authors named "C D Leonardo"

Background  The generation of innovative research ideas is crucial to advancing the field of medicine. As physicians face increasingly demanding clinical schedules, it is important to identify tools that may expedite the research process. Artificial intelligence may offer a promising solution by enabling the efficient generation of novel research ideas.

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Background: Inguinal lymph node (LN) dissection (iLND) is mandatory in cN2 penile squamous cell carcinoma (PSCC). Open iLND (OIL) is often omitted due to the high rate of complications. A minimally invasive approach may reduce morbidity; however, evidence supporting its role to treat bulky nodes is limited.

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This article compares surgical and survival outcomes of robot-assisted and open radical cystectomy with cutaneous ureterostomy for the treatment of frail bladder cancer patients with limited life expectancy. The institutional database was searched for cystectomy cases with cutaneous ureterostomy, from 1 June 2016 to 31 August 2022. The study population was split into two groups, according to the surgical approach.

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Article Synopsis
  • Cardiac resynchronization therapy (CRT) using biventricular (BIV) pacing is aimed at heart failure patients but some don't respond; MultiPoint Pacing (MPP) might offer better results for these non-responders.
  • In a study with 3724 patients treated with BIV, 1639 were identified as non-responders and some were randomized to MPP or continued BIV pacing.
  • Results showed MPP led to better outcomes with a 33% success rate in reducing heart failure events compared to 23.5% in BIV, and MPP also resulted in fewer hospitalizations for heart failure.
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Importance: Evidence on prostate cancer (PCa) in transgender women is very limited; data are needed to reduce gender disparities in both PCa knowledge and health care.

Objective: To evaluate the prevalence of PCa among transgender women in the US and assess the factors associated with PCa, and factors associated with biochemical recurrence (BCR) and bone metastases (BM) secondary to PCa in the transgender population.

Design, Setting, And Participants: A retrospective cohort study was conducted in October 2023, covering the period between 2011 and 2022 (12-year analysis).

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