Publications by authors named "C D Kaminski"
The Antarctic seabed harbors significant biodiversity, and almost 90% of oceanic environments are permanently below 5 °C (i.e., deep sea and polar regions).
View Article and Find Full Text PDFBackground: Whole blood (WB) resuscitation has been shown to provide mortality benefit. However, the impact of whole blood transfusions on the risk of venous thromboembolism (VTE) remains unclear. We sought to compare the VTE risk in patients resuscitated with WB vs component therapy (COMP).
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- During neurogenesis, an initially excessive number of neurons are formed in the nervous system, but many are later eliminated through a process called apoptosis, or programmed cell death.
- This elimination is influenced by targets of innervation, which produce neurotrophic factors that help maturing neurons survive and grow as they connect with these targets.
- Research in mice shows that while neurogenesis and apoptosis typically complete within the first few days after birth, both processes continue significantly longer, indicating neurogenesis may play a role in replacing neurons lost during synaptic refinement.
Membrane-less compartments and organelles are widely acknowledged for their role in regulating cellular processes, and there is an urgent need to harness their full potential as both structural and functional elements of synthetic cells. Despite rapid progress, synthetically recapitulating the nonequilibrium, spatially distributed responses of natural membrane-less organelles remains elusive. Here, we demonstrate that the activity of nucleic-acid cleaving enzymes can be localized within DNA-based membrane-less compartments by sequestering the respective DNA or RNA substrates.
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- - The study examines the benefits of a peptide extract from the sea cucumber *Apostichopus japonicus* (Sample-P) in enhancing skin cell function and healing, especially under oxidative stress caused by environmental damage.
- - Sample-P shows antioxidative properties and promotes cell migration, while also preventing severe cellular stress responses, indicated by mTOR expression levels.
- - Proteomics analysis reveals that Sample-P affects critical protein pathways related to ribosome function and protein processing, which together help maintain DNA integrity and protect cellular components under stress, highlighting its potential for treating wounds and aging skin.