Publications by authors named "C D Gillespie"
Introduction: Given its proximity to the central nervous system, surgical site infections (SSIs) after craniotomy (SSI-CRAN) represent a serious adverse event. SSI-CRAN are associated with substantial patient morbidity and mortality. Despite the recognition of SSI in other surgical fields, there is a paucity of evidence in the neurosurgical literature devoted to skin closure, specifically in patients with brain tumors.
View Article and Find Full Text PDFCranioplasty is an operation that aims to repair a defect in the skull. Indications commonly include Traumatic Brain Injury (TBI), tumours, and infections. It carries a high rate of postoperative morbidity.
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- Deep Brain Stimulation (DBS) and Motor Cortex Stimulation (MCS) are invasive therapies used to treat neuropathic pain like Central Post-Stroke Pain, but there's been no thorough comparison of their effectiveness using standardized pain metrics.
- A systematic review and meta-analysis were conducted, reviewing 32 studies (330 patients) and measuring pain relief through VAS and NRS scores, finding that MCS had a slightly better improvement rate compared to DBS.
- Despite showing MCS as potentially more effective, further studies are needed to establish the best surgical approach for treating Central Post-Stroke Pain.
Recruiting and retaining research participants is challenging because it often requires overcoming structural barriers and addressing how histories of mistrust and individuals' lived experiences affect their research engagement. We describe a pilot workshop designed to educate clinical research professionals on using empathy skills to recognize and mitigate bias to improve recruitment and retention. In a post-workshop survey (22/31 participants completed), 94% agreed the workshop helped them practice perspective-taking, recognize implicit bias, and identify opportunities for empathy.
View Article and Find Full Text PDFObjective: Hyponatremia after aneurysmal subarachnoid hemorrhage (aSAH) is common, however the incidence, and association with vasospasm, morbidity, and mortality, has yet to be defined. We aimed to identify incidence of hyponatremia after aSAH, and quantify its association with measurable outcomes.
Methods: A PRISMA-compliant systematic review and meta-analysis was conducted (PROSPERO ID CRD42022363472).