Publications by authors named "C D Cushman"
Article Synopsis
- The musculoskeletal system is prone to joint pain from conditions like rheumatoid arthritis and osteoarthritis, prompting the exploration of peptides as a new treatment option that is safe and minimally invasive.
- This study reviews existing oral and intra-articular peptide therapies, focusing on their effectiveness for soft tissue regeneration and comparing their delivery routes.
- The review found that both oral and intra-articular peptides can aid in soft tissue repair, but each has its own challenges of bioavailability, and more research is needed to establish their efficacy before they are widely adopted as an alternative to surgery.
A 41-year-old male with a history of tobacco and alcohol use presented to our clinic for a follow up of an incidentally diagnosed splenic mass. The patient was sent for further diagnostic evaluation, and computed tomography showed a large splenic mass with heterogenous enhancement raising concern for neoplasm. Due to the uncertain nature of the splenic lesion and high complication rate of percutaneous splenic biopsy, a splenectomy was performed.
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- Visceral artery pseudoaneurysms, especially in the gastroduodenal artery, are rare but can lead to severe complications like rupture, particularly in patients with chronic pancreatitis.
- A 61-year-old man with chronic pancreatitis and other health issues was found to have a 7 cm pseudoaneurysm that was successfully treated using coil embolization after presenting with abdominal pain and fevers.
- This case emphasizes the need for quick diagnosis and treatment of GDA pseudoaneurysms and shows that endovascular therapies can effectively enhance outcomes in complex cases linked to chronic pancreatitis.
Arteriovenous malformations (AVMs) are rare vascular anomalies that present complex diagnostic and therapeutic challenges, particularly in uncommon locations such as the lower extremities. A 72-year-old female with chronic atrial fibrillation, hypertension, and peripheral vascular disease presented with severe lower extremity edema due to multiple AVMs below the knee. This case underscores the importance of a multidisciplinary, individualized approach in managing complex AVMs and highlights the need for advanced imaging and diverse interventional techniques to ensure effective treatment and long-term outcomes.
View Article and Find Full Text PDFKey Clinical Message: Merkel cell carcinoma (MCC) presents challenges in surveillance due to varied recurrence rates and uncertain follow-up protocols, especially in late recurrent cases. These cases need personalized monitoring strategies beyond traditional timelines, such as clinical and molecular factors, in order to optimize patient outcomes.
Abstract: Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer with neuroendocrine differentiation with a propensity for recurrence following initial treatment.