Clinical-Radiological Correlation of Retained Silicone Sponge Presenting as Orbital Inflammation.

A 32-year-old female who underwent scleral buckle removal presented 5 weeks postoperatively with a red, fluctuant subconjunctival mass. CT scan identified an irregularly bordered, hypoattenuated lesion next to the globe with the density of air. Ophthalmic plastic and reconstructive surgeons were consulted to evaluate orbital cellulitis with intraorbital gas, at which point it was deemed that the hypoattenuated mass was likely a retained sponge element based on its radiological features.

A diffusible factor from normal retinal cells promotes rod photoreceptor survival in an in vitro model of retinitis pigmentosa.

Transgenic mice expressing a dominant mutation in the gene for the phototransduction molecule rhodopsin undergo retinal degeneration similar to that experienced by patients with the retinal degenerative disease, retinitis pigmentosa (RP). Although the mutation is thought to cause photoreceptor degeneration in a cell-autonomous manner, the fact that rod photoreceptor degeneration is slowed in chimeric wild-type/mutant mice suggests that cellular interactions are also important for maintaining photoreceptor survival. To more fully characterize the nature of the cellular interactions important for rod degeneration in the RP mutant mice, we have used an in vitro approach.

Digital palpation of intraocular pressure.

Background And Objective: Previous studies investigating the accuracy of digital palpation through the eyelids to estimate intraocular pressure (IOP) have shown disappointing results. In this study, the accuracy of digital assessment of IOP by palpation of the bare cornea is investigated.

Materials And Methods: The IOP of a cadaveric eye model was varied from 5 to 40 mm Hg in increments of 5 mm Hg.

Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus.

Background: Fundus flavimaculatus (Stargardt disease) is a group of inherited macular dystrophies in which central vision usually decreases in the first two decades of life. Previous histopathologic studies used light, scanning, and transmission electron microscopy to characterize the retinal pigment epithelium (RPE) in fundus flavimaculatus. The authors describe in detail the pathologic changes in the neurosensory retina, including use of specific immunocytochemical markers.