Publications by authors named "C D Baroni"

Objective: To assess the prevalence and the characteristics of pelvic floor dysfunction (PFD) in women with endometriosis.

Methods: This is a methodological paper that describes the 'Endometriosis and Pelvic Floor Dysfunction' (EndoPFD) multicenter study protocol. It involves three sites: the University Hospital of Pisa, the San Raffaele Hospital of Milan and the Vanvitelli University Hospital of Naples.

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  • - Lasamide, a synthetic byproduct of the diuretic Furosemide manufacturing, is highlighted as a valuable component for drug discovery techniques.
  • - Researchers tested Lasamide's effectiveness in inhibiting human Carbonic Anhydrases (hCAs) using a stopped-flow method and examined its binding through X-ray crystallography.
  • - The study introduces a new crystal form for a specific Carbonic Anhydrase mimic (hCA IX), which is discussed in detail.
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Microsatellites are widely used in population genetics, but their evolutionary dynamics remain poorly understood. It is unclear whether microsatellite loci drift in length over time. This is important because the mutation processes that underlie these important genetic markers are central to the evolutionary models that employ microsatellites.

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  • - Pulmonary atelectasis is a common issue during anesthesia, and mechanical ventilation along with alveolar recruitment maneuvers (ARMs) and positive end-expiratory pressure (PEEP) can help improve lung function, despite the risk of lung injuries like volutrauma and barotrauma.
  • - The study aimed to assess how lung volume distribution changes with different levels of PEEP during ARMs in 12 anesthetized dogs, using CT scans for detailed monitoring.
  • - Results showed that ARMs significantly improved lung ventilation and static compliance, especially at specific PEEP levels (10 and 5 cmHO), while also affecting cardiovascular measures like heart rate and mean arterial blood pressure.
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