Publications by authors named "C D Atkins"
Background: La Crosse virus neuroinvasive disease (LACVND) is the most common cause of arboviral encephalitis in children within the United States; in North Carolina, it is the most prevalent endemic mosquito-borne disease in humans.
Methods: Here we report a surveillance summary of confirmed and probable LACVND during 2000-2020 using North Carolina Electronic Disease Surveillance System data, and we describe associated demographic characteristics, spatiotemporal distribution, clinical features, and mortality rates.
Results: A total of 355 cases (74.
Article Synopsis
- Mulibrey nanism (MN) is a rare genetic disorder affecting growth and causing serious health issues, with about 150 cases identified globally since 1973.
- A case study of a male toddler with MN showed symptoms like hypoxia and swelling, leading to a complex diagnostic process that confirmed restrictive cardiomyopathy through invasive testing.
- The case emphasizes the challenges of diagnosing restrictive cardiomyopathy using echocardiography and underscores the importance of a multidisciplinary, family-centered treatment approach for this condition.
In recent years, significant advances have been made in the study of mild traumatic brain injury (mTBI). Complete recovery from mTBI normally requires days to weeks, yet a subset of the population suffers from symptoms for weeks to months after injury. The risk factors for these prolonged symptoms have not yet been fully understood.
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- The Society of Thoracic Surgeons Congenital Heart Surgery Database is a major global resource on congenital heart surgeries, but lacks data on complications, comorbidities, and long-term patient outcomes.
- This study assessed how effectively this database could be linked to hospital electronic health records in North Carolina and Georgia, using both indirect and direct identifiers.
- Results showed that indirect linkage matched 79% of admissions, while direct methods achieved up to 99.5% success, demonstrating the effectiveness of integrating surgical data with electronic records for better patient care insights.
Neuroactive steroids reduce mortality, decrease edema, and improve functional outcomes in preclinical and clinical traumatic brain injury (TBI) studies. In this study, we tested the efficacy of two related novel neuroactive steroids, NTS-104 and NTS-105, in a rat model of TBI. NTS-104 is a water-soluble prodrug of NTS-105, a partial progesterone receptor agonist.
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