The use of methotrexate for treatment of inflammatory bowel disease in clinical practice.

Background: Methotrexate is considered a treatment for Crohn's disease, whilst few data in ulcerative colitis are available.

Aim: To evaluate frequency, indications, efficacy and safety of methotrexate in inflammatory bowel disease patients.

Methods: 5420 case histories were reviewed.

Pre-illness changes in dietary habits and diet as a risk factor for inflammatory bowel disease: a case-control study.

Aim: To evaluate whether symptoms of inflammatory bowel disease (IBD), before diagnosis modify dietary habits, and to investigate the pre-illness diet in patients with recent IBD in comparison with an age-matched healthy control group.

Methods: Overall, 83 new cases of IBD (41 ulcerative colitis, 42 Crohn's disease) and 160 healthy controls were studied. Portions per week of 34 foods and beverages before onset of symptoms were recorded using a validated questionnaire.

Incidence and risk factors for gallstones in patients with inflammatory bowel disease: a large case-control study.

Unlabelled: The risk for gallstones (GD) in inflammatory bowel diseases and the factors responsible for this complication have not been well established. We studied the incidence of GD in a cohort of Crohn's disease (CD) and ulcerative colitis (UC) patients and investigated the related risk factors. A case-controlled study was carried out.