In recent years there has been an increasing interest in Building-Integrated Photovoltaic (BIPV) and Building-Integrated Photovoltaic/Thermal (BIPVT) systems since they produce clean energy and replace conventional building envelope materials. By taking into account that storage is a key factor in the effective use of renewable energy, the present article is an overview about storage systems which are appropriate for BIPV and BIPVT applications. The literature review shows that there are multiple storage solutions, based on different kinds of materials (batteries, Phase Change Material (PCM) components, etc.
View Article and Find Full Text PDFIt is well recognized that the non-canonical DNA structures known as G-quadruplexes (G4s) have a potential anticancer significance and several compounds have been discovered and evaluated as promising G4 binders with anticancer activity. Here, starting from a promising hit with an indolo-naphthyridine scaffold, a small series of five indolo-naphthyridine based derivatives have been designed and evaluated as G4-targeting compounds. FRET biophysical studies were performed on multiple DNA G4 structures, leading to the identification of a multi-target G4 stabilizer with a slight preference for the c-KIT1 and a good G4 over duplex selectivity.
View Article and Find Full Text PDFThe present article assesses the environmental profile of a real-scale anaerobic-digestion plant that has been developed in France. The system utilises 13652 t of different types of feedstock related to food industry, agriculture, etc. The study is based on Life Cycle Assessment (LCA) according to Global Warming Potential (GWP), Cumulative Energy Demand (CED), ReCiPe midpoint/endpoint and USEtox.
View Article and Find Full Text PDFEGFR is an oncogene that encodes for a trans-membrane tyrosine kinase receptor. Its mis-regulation is associated to several human cancers that, consistently, can be treated by selective tyrosine kinase inhibitors. The proximal promoter of EGFR contains a G-rich domain located at 272 bases upstream the transcription start site.
View Article and Find Full Text PDFThe purpose of the present article is the evaluation, by means of life cycle assessment, of a system which consists of vacuum-tube solar thermal collectors. The system is appropriate for building integration and it has been developed in France. The methods ReCiPe and USEtox have been adopted.
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