Publications by authors named "C Couffignal"
Background: We aimed to investigate the association of intracranial complications diagnosed on neuroimaging with neurological outcomes of adults with severe pneumococcal meningitis.
Methods: We performed a retrospective multicenter study on consecutive adults diagnosed with pneumococcal meningitis requiring at least 48 h of stay in the intensive care unit (ICU) and undergoing neuroimaging, between 2005 and 2021. All neuroimaging were reanalyzed to look for intracranial complications which were categorized as (1) ischemic lesion, (2) intracranial hemorrhage (3) abscess/empyema, (4) ventriculitis, (5) cerebral venous thrombosis, (6) hydrocephalus, (7) diffuse cerebral oedema.
Article Synopsis
- The study examines the occurrence and location of coronary artery disease (CAD) in adults with anomalous aortic origin of a coronary artery (AAOCA), which is not well documented.
- Researchers analyzed data from 390 patients, focusing on the presence of CAD through imaging techniques like coronary angiography.
- The findings revealed that CAD is more prevalent in the proximal segment of retroaortic AAOCA compared to other types of AAOCA, with no CAD found in the proximal segment of interarterial AAOCA, and the reasons for these differences remain unclear.
Introduction: Physical restraint (PR) is prescribed in patients receiving invasive mechanical ventilation in the intensive care unit (ICU) to avoid unplanned removal of medical devices. However, it is associated with an increased risk of delirium. We hypothesise that a restrictive use of PR, as compared with a systematic use, could reduce the duration of delirium in ICU patients receiving invasive mechanical ventilation.
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- The study investigates the effects of SARS-CoV-2 infection in pregnant women during their 2nd and 3rd trimesters, focusing on outcomes for both mothers and newborns during the first two COVID-19 waves in Paris from April 2020 to January 2021.
- Conducted in 10 maternity hospitals, the research included 2,410 pregnant women, with 310 testing positive for the virus, mostly around 28 to 37 weeks of gestation, and found that many could be treated as outpatients, while 23% required hospitalization.
- Key findings revealed that multiparous women were more likely to have serious outcomes such as preterm delivery and an
This psychometric pilot study aims to evaluate a new multidimensional simple scale, named the nightmare severity index (NSI) - close to the existing insomnia (ISI) and hypersomnia (HSI) severity indexes. The NSI encompasses all main dimensions of nightmare disorder, evaluating four subdimensions: frequency, emotional impact, diurnal impact, and nocturnal impact of nightmares. The NSI was completed by a total of 102 patients.
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