Publications by authors named "C Costalos"
Background: Post-natal gut maturation in infants interrelates maturation of the morphology, digestive, and immunological functions and gut microbiota development. Here, we explored both microbiota development and markers of gut barrier and maturation in healthy term infants during their early life to assess the interconnection of gut functions during different infant formulae regimes.
Methods: A total of 203 infants were enrolled in this randomized double-blind controlled trial including a breastfed reference group.
Background: In the absence of breast-feeding and its immunomodulatory factors, supplementation of starter infant formula (IF) with probiotics is currently used to support immune functions and gut development.
Aim: To assess whether immune-related beneficial effects of regular dose (10(7) CFU/g of powder) of the probiotic Bifidobacterium lactis CNCM I-3446 (hereafter named B. lactis) in starter IF supplementation can be maintained with starter IF containing a low dose (10(4) CFU/g of powder) of B.
Background: Gut hormones play an important role in the adaptation of the immature neonatal gut, and their secretion may be modulated by prebiotics. Furthermore, prebiotics are well known for their hypolipidemic potentials. We tested the hypothesis that prebiotics could alter motilin and gastrin secretion and reduce lipids in healthy preterms.
View Article and Find Full Text PDFObjective: To identify maternal age trends in Greece over a 29-year period from 1980 to 2008.
Study Design: Data concerning live births after 24 gestational weeks was collected from the Hellenic Vital Statistics records and analyzed. Mothers were categorized into age groups.