High relative risk of a second pulmonary cancer in patients affected by laryngeal cancer: differences by specific site of occurrence and lung cancer histotype.

The frequency of a second primary lung tumor in patients affected by laryngeal cancer has been evaluated on the basis of 128,532 biopsies and 27,753 autopsies carried out from January 1, 1979 through December 31, 1988. Among these cases, 432 laryngeal cancers and 44 synchronous or metachronous pulmonary cancers have been detected (7 during life, 37 at autopsy). The highest risk of developing a lung tumor has been evidenced in patients affected by supraglottic cancer during the first 2 years of follow-up (relative risk [RR]: 32.

Supraglottic versus glottic laryngeal cancer: epidemiological and pathological aspects.

Between 1979 and 1988, 432 cases of previously untreated laryngeal cancers were histologically diagnosed at the Institute of Pathological Anatomy of the University of Trieste. Of these cases, 192 were supraglottic and 182 glottic cancers. The overall crude incidence was 31.

[Pulmonary embolism: epidemiologic analysis of 27,410 autopsies during a 10-year period].

The frequency of pulmonary embolism (PE) among all patients at necropsy in a university hospital from 1979 through 1988 has been evaluated. Of 27,410 subjects, 1,984 males (14.6%) and 3,428 females (24.

[Primary adenocarcinoma of the bladder].

A clinicohistopathological study of 12 cases of primary adenocarcinoma of the bladder diagnosed over an 11 year period is presented. Six of these were pure adenocarcinomas, while the remainder consisted of 2 adenocarcinoma with transitional malignant elements, 2 adenosquamous carcinomas and 2 mesonephric adenocarcinomas. The biological behaviour of these neoplasms was particularly aggressive: in none of the cases was the neoplasm limited to the bladder epithelium, but was generally seen to have infiltrated the muscular wall.

[Basal cell epithelioma of the lip. Analysis of 42 cases].

Basal cell epithelioma of the lip. An analysis of 42 cases. The authors carried out a histopathological and epidemiological study of 42 basal cell epitheliomas of the lip.