Publications by authors named "C Corrado"

Background/objective: Assessing Orthostatic Intolerance (OI, symptoms upon standing from supine) is recommended in athletes with sport-related concussions (SRCs), as this is caused by impairments in the cardiovascular autonomic nervous system (cANS). Early Exercise Intolerance (Early EI, symptoms on light physical exertion) is also due to impairments in the cANS but is difficult to incorporate into outpatient clinical practice (cost of personnel, time, equipment). The purpose of this study was to determine if we could use OI to screen for Early EI, as well as understand differences between adolescents who do and do not report OI.

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Urinary tract infections (UTIs) are common bacterial infections in children. UTIs may be limited to the bladder or involve the kidneys with possible irreversible damage. Congenital abnormalities of the kidney and urinary tract (CAKUT) are often associated with UTIs; kidney scars have been considered a consequence of untreated UTIs but may be congenital.

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Article Synopsis
  • Researchers looked at children in Italy who were hospitalized for a urinary infection and checked their sodium (Na) and potassium (K) levels.
  • They found that 23% of the kids had low sodium, while some had high potassium or both low sodium and high potassium.
  • The study also discovered that specific levels in the blood and age were linked to these imbalances, with the most common issue being low sodium.
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  • * The study explored the effects of a natural compound combination (escin-bromelain-ginkgo biloba-sage miltiorrhiza, or EBGS) on inhibiting platelet adhesion to damaged blood vessels, a crucial step in thrombus formation.
  • * Results indicated that EBGS pretreatment reduces platelet adhesion by inhibiting adhesion molecules and inflammatory cytokines, suggesting its potential as a preventive therapy against thrombus formation.
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Article Synopsis
  • This Special Issue focuses on key topics in cellular signaling transduction, highlighting its importance in understanding biological processes.
  • It emphasizes that studying regulatory networks is crucial for improving disease prevention, diagnosis, and treatment.
  • The aim is to explore how these networks influence therapeutic responses and the balance of bodily functions, known as homeostasis.
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