Publications by authors named "C Confavreux"
Antibodies against Ku have been described in patients with various connective tissue diseases. The objective of this study was to describe the clinical, functional, and imaging characteristics of interstitial lung disease in patients with anti-Ku antibodies. : This single-center, retrospective observational study was conducted at a tertiary referral institution.
View Article and Find Full Text PDFBackground: In spite of spectacular advances in the treatment of multiple myeloma, a majority of patients will die from this disease or related complications. While a great amount of focus has been dedicated to the development of novel therapies, little attention has been paid to latter stages of patient follow-up.
Patients And Methods: In order to describe patient management during this critical period as well as the immediate causes and circumstances of death, we have analyzed a single center series of 100 patients diagnosed with myeloma who died between 2016 and 2021.
Article Synopsis
- The study aimed to compare the antibody response to SARS-CoV-2 in patients with inflammatory rheumatic diseases and healthy individuals.
- Researchers screened unvaccinated patients with conditions like rheumatoid arthritis, spondyloarthritis, and psoriatic arthritis in France, and matched them with seropositive healthcare workers as controls.
- Results showed no significant difference in antibody levels between both groups, with a trend indicating that patients with severe COVID-19 symptoms had higher antibody titres; treatments like glucocorticoids seemed linked to lower antibody responses.
Article Synopsis
- The study investigates mineral bone disorder in patients with chronic kidney disease after kidney transplantation, focusing on bone biomarkers and microarchitecture changes before and 6 months after the surgery.
- A subgroup of patients aged 10 to 18 who underwent their first kidney transplant was compared to healthy controls, revealing initially higher bone densities but notable declines in trabecular microarchitecture at the radius six months post-transplant.
- Despite some improvements in bone health, many patients persisted with metabolic issues like acidosis and elevated parathyroid hormone levels after the transplant, indicating ongoing bone metabolism concerns.