Publications by authors named "C Cigala"
Background: CA19.9 is the unique marker recommended for the preoperative staging and the follow-up of patients suffering from pancreatic ductal adenocarcinoma (PDAC) but up to 30% of PDAC patients maintain normal CA19.9 values and cannot be monitored in this way.
View Article and Find Full Text PDFArticle Synopsis
- An inflammatory pseudotumor of the liver is a rare lesion that resembles cancer but is caused by inflammation, with no known cause and vague symptoms making diagnosis difficult.
- Research involving 69 cases indicates that imaging is often non-specific and biopsies are not commonly performed, despite their importance for diagnosis.
- Current treatment trends lean towards conservative management, but surgical intervention is still the preferred option for uncertain diagnoses, highlighting the need for a collaborative approach in treatment planning.
Article Synopsis
- NK cells are crucial for monitoring and controlling the development of hepatocellular carcinoma (HCC) through interactions with the NKG2D receptor and its ligand MICA/B.
- Research compared NK cell function in patients with cirrhosis and HCC, those with cirrhosis alone, and healthy donors, showing that IL-15 stimulation could enhance NK cell activity that is otherwise reduced in HCC patients.
- The study suggests that combining anti-MICA/B monoclonal antibodies with IL-15 stimulation could enhance NK cell responses, offering a potential new approach for HCC immunotherapy.
The original version of this article unfortunately contained a mistake. All the authors first name and second name has been inadvertently interchanged. Now the authors name are corrected.
View Article and Find Full Text PDFBackground And Aims: Hepatobiliary phase (HBP) Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) has increased the accuracy in differentiating focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA). However, the ability of this technique to distinguish HCA subtypes remains controversial. The aim of this study was to investigate the expression of hepatocyte transporters (OATPB1/B3, MRP2, MRP3) in HCA subtypes, hence to understand their MRI signal intensity on HBP Gd-EOB-DTPA-enhanced MRI.
View Article and Find Full Text PDF