Publications by authors named "C Chico"
Effect of a bundle intervention on adherence to quality-of-care indicators and on clinical outcomes in patients with Staphylococcus aureus bacteraemia hospitalized in non-referral community hospitals.
J Antimicrob Chemother
November 2024
Background: Although a significant number of cases of Staphylococcus aureus bacteraemia (SAB) are managed at non-referral community hospitals, the impact of a bundle-of-care intervention in this setting has not yet been explored.
Methods: We performed a quasi-experimental before-after study with the implementation of a bundle of care for the management of SAB at five non-referral community hospitals and a tertiary care university hospital. Structured recommendations for the five indicators selected to assess quality of care were provided to investigators before the implementation of the bundle and monthly thereafter.
Outpatient intravenous antimicrobial therapy in men with febrile urinary tract infections: differences between the hospital admission-avoidance and early-discharge models.
Emergencias
October 2021
Article Synopsis
- The study examined epigenetic age acceleration (EAA) in head and neck cancer patients during and after treatment, focusing on its relationship with inflammation and fatigue.
- Results showed a significant increase in EAA of about 4.9 years right after radiotherapy, with higher fatigue levels linked to greater EAA, particularly in patients with severe fatigue.
- Inflammation markers, like C-reactive protein and interleukin-6, were also associated with increased EAA, suggesting they play a role in the relationship between EAA and patient fatigue.
Purpose: Recent evidence supports a key role of gut microbiome in brain health. We conducted a pilot study to assess associations of gut microbiome with cancer-related fatigue and explore the associations with DNA methylation changes.
Methods: Self-reported Multidimensional Fatigue Inventory and stool samples were collected at pre-radiotherapy and one-month post-radiotherapy in patients with head and neck cancer.
Cancer patients experience a cluster of co-occurring psychoneurological symptoms (PNS) related to cancer treatments. The gut microbiome may affect severity of the PNS via neural, immune, and endocrine signaling pathways. However, the link between the gut microbiome and PNS has not been well investigated in cancer patients, including those with head and neck cancers (HNCs).
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