Publications by authors named "C Chelazzi"

Article Synopsis
  • * Conducted across 24 sites in ten countries, 1200 cancer patients on opioid analgesics completed questionnaires assessing their constipation status, revealing that 59.5% met the criteria for OIC, but only 61.5% self-reported experiencing constipation.
  • * Results indicated that while 72% were prescribed laxatives or other treatments, only 66% consistently used them, leading to inadequate management of OIC due to poor assessment and treatment follow-up.
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Background: This phenomenological-hermeneutic study is about the experiences of physicians in the Oncology Intensive Care Unit of the Careggi University Hospital, in Florence. The Oncology Intensive Care Unit is a place of great emotional impact and can be create stressful situations. The emotional labor can lead to the development of cynicism, depersonalization and emotional exhaustion.

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Experimental and observational studies have shown that opioid analgesics may increase tumor growth, potentially reduce immunotherapy efficacy, and shorten survival. As a result of the lack of clinical data, the current rationale for continuing opioid analgesic treatment is based on animal models, which suggests that physical pain itself may potentially influence cancer growth and exert immunosuppressive effects. Total pain encompasses the various factors that patients may experience during their cancer journey: physical symptoms, social isolation/loneliness, psychological, spiritual/existential, and financial distress.

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Palliative care, with its focus on comprehensive patient assessment encompassing physical, social, emotional, and spiritual pain, plays a crucial role in modern medicine. Despite its significance, integration with oncology and other healthcare specialties often occurs late in the disease trajectory. Strategies to bridge this gap include considering a "rebranding" of palliative care to "supportive care.

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