Functional Characterization of the Gene from and Its Role in Abiotic Stress Tolerance in Transgenic .

The frequent occurrence of extreme weather conditions in the world has brought many unfavorable factors to plant growth, causing the growth and development of plants to be hindered and even leading to plant death, with abiotic stress hindering the growth and metabolism of plants due to severe uncontrollability. The WHY1 transcription factor plays a critical role in regulating gene expression in plants, influencing chlorophyll biosynthesis, plant growth, and development, as well as responses to environmental stresses. The important role of the gene in regulating plant growth and adaptation to environmental stress has become a hot research topic.

A Spiro-Based NIR-II Photosensitizer with Efficient ROS Generation and Thermal Conversion Performances for Imaging-Guided Tumor Theranostics.

Organic photosensitizers (PSs) possessing NIR-II emission and photodynamic/photothermal effect have received a great sense of attention for their cutting-edge applications in imaging-guided multimodal phototherapy. However, it is highly challenging to design efficient PSs with high luminescence and phototherapy performance simultaneously. In this study, a spiro-functionalization strategy is proposed to alleviate aggregate-caused quenching of PSs and promote photodynamic therapy, and the strategy is verified via a spiro[fluorine-9,9'-xanthene]-modified NIR-II PS (named SFX-IC) with an acceptor-donor-acceptor configuration.

Smartphone-based non-invasive detection of salivary uric acid based on the fluorescence quenching of gleditsia sinensis carbon dots.

A smartphone-based non-invasive method was developed for salivary uric acid detection using Gleditsia Sinensis carbon dots (GS-CDs). The GS-CDs synthesized by the one-pot hydrothermal method emitted blue fluorescence at a maximum excitation wavelength of 350 nm and had good fluorescence stability in the presence of different ions, while showing selectivity to uric acid solution. The ability of uric acid (UA) to quench the fluorescent substances present in the GS-CDs, was confirmed through HPLC-FLD and LC-MS, FTIR and XPS.

Association between various blood glucose variability-related indicators during early ICU admission and 28-day mortality in non-diabetic patients with sepsis.

Background: Various blood glucose (BG) variability-related indexes have been widely used to assess glycemic control and predict glycemic risks, but the association between BG variations and prognosis in non-diabetic patients with sepsis remains unclear.

Methods: The single-center retrospective cohort study included 7,049 non-diabetic adults with sepsis who had at least 3 records of bedside capillary point of care BG testing during the first day after ICU admission from MIMIC-IV database (2008 to 2019). Coefficient of variation and standard deviation of glucose (i.