Publications by authors named "C Chakvetadze"
Antibiotic prescription in ambulatory care for COVID-19 patients: a cohort analysis in four European countries.
Eur J Clin Microbiol Infect Dis
January 2024
Article Synopsis
- Objective: The study aims to analyze and compare antibiotic prescription rates for COVID-19 patients among general practitioners in France, the UK, Belgium, and Romania by examining 4.5 million electronic prescribing records.
- Methods: Researchers evaluated antibiotic prescription data from 3,656 GPs across the four countries, looking specifically at rates during COVID-19 consultations and categorizing the types of antibiotics prescribed.
- Results: France and Belgium showed higher overall prescription rates (6.66% and 7.46%), with significant variation in prescribing patterns, notably in Romania where a majority of GPs prescribed antibiotics despite lower overall rates, and a notable preference for azithromycin in all countries except the UK.
Introduction: Antimicrobial resistance is a major healthcare issue responsible for a large number of deaths. Many reviews identified that PKPD data are in favor of the use of continuous infusion, and we wanted to review clinical data results in order to optimize our clinical practice.
Methodology: We reviewed Medline for existing literature comparing continuous or extended infusion to intermittent infusion of betalactams.
Background: The use of long acting injectable (LAA) antiretroviral drugs may be an alternative option for HIV treatment and prevention. Our study focused on patient perspectives to understand which individuals, among people with HIV (PWH) and pre-exposure prophylaxis (PrEP) users, would constitute the preferential target for such treatments in terms of expectations, tolerability, adherence and quality of life.
Methods: The study consisted in one self-administrated questionnaire.
Open lower limb fractures are common injuries, and the occurrence of infectious complications after open fractures is a usual problem. The rate of surgical site infections (SSIs) and the nature and resistance of the germs responsible for SSIs remain poorly described. Our aim was to describe the bacterial epidemiology of SSIs after surgical management of an open lower limb fracture.
View Article and Find Full Text PDFPurpose: This is a subanalysis of a previous study which compared the effectiveness of trimetoprim-sulfametoxazole (TMP-SMX) with all other regimens for treatment of ventilator-associated pneumonia (VAP). Aim of the current study was to focus on the effectiveness of a strategy based on TMP-SMX as de-escalation from β-lactam including regimens.
Methods: Retrospective cohort study including patients who were hospitalized for VAP from 2011 to 2019.