Publications by authors named "C Cervera"
Article Synopsis
- - A study in Alberta from 2022-2023 highlighted cases of Bartonella quintana infection transmitted through solid organ transplants (SOT) from unhoused deceased donors (UDDs), with a notable attack rate of 12.5% among recipients.
- - Out of 32 organ recipients from seropositive donors, 6 developed skin-related symptoms of bartonellosis, with the majority showing positive serology results for Bartonella.
- - This incident underscores the risk of unexpected infections from donors with a history of substance use, emphasizing the need for vigilance among clinicians regarding potential transmission through organ transplants.
Background: We report results from the national CLEAR (Canadian Leadership on Antimicrobial Real-Life Usage) registry on the usage of ceftolozane/tazobactam in Canada from 2022 to 2024.
Research Design And Methods: The authors reviewed the final data using the national ethics approved CLEAR study. Thereafter, the literature is surveyed regarding the usage of ceftolozane/tazobactam to treat patients with HABP and VABP via PubMed (up to May 2024).
Background: There are few interventional studies using CMV cell-mediated immunity (CMI) to guide antiviral prophylaxis. We assessed the Quantiferon-CMV (QTF-CMV) assay to guide CMV prophylaxis duration in high-risk organ transplant recipients.
Methods: A single-arm, multicenter, prospective interventional study including high-risk kidney, pancreas, liver, and heart transplant recipients who were either donor CMV-seropositive, recipient-seronegative (D+/R-) or recipient-seropositive with antithymocyte globulin (R+/ATG) induction.
Background: Cytomegalovirus (CMV) mismatched, donor IgG-positive/recipient IgG-negative, solid organ transplant recipients (SOTRs) are at high risk of CMV invasive disease. Post-prophylaxis disease is an issue in this population. Some programs employ surveillance after prophylaxis (SAP) to limit the incidence of post-prophylaxis disease.
View Article and Find Full Text PDFThe impact of colonization by multidrug resistant bacteria on graft survival, risk of infection, and mortality in recipients of solid organ transplant: systematic review and meta-analysis.
Clin Microbiol Infect
October 2024
Background: The Global increase in colonization by multidrug-resistant (MDR) bacteria poses a significant concern. The precise impact of MDR colonization in solid organ transplant recipients (SOTR) remains not well established.
Objectives: To assess the impact of MDR colonization on SOTR's mortality, infection, or graft loss.