Surgical-related Morphological Characteristics of Sphenoid Sinuses: A Comprehensive CT-Based Analysis.

Background: This study aims to assess the relationships between sphenoid sinus (SS) types, septation, lobulation, symmetry, septal deviation, and the variations in SS pneumatization regarding the surrounding neurovascular structures using Computed tomography (CT) images. Sexes and age groups were investigated.

Material And Methods: We retrospectively evaluated head CT-scans of 320 patients (age range 18-49 years); mean of 43.

Immunogenicity of a recombinant chimera composed of CROP domain segments from the hemorrhagic and lethal toxins of Paeniclostridium sordellii.

Paeniclostridium sordellii is responsible for severe infections in horses, cattle, and sheep, however, conventional vaccines exhibit limitations in production and immunogenicity. This study assessed the immunogenicity of a recombinant bacterin composed of a chimera (rQTcsHL) that combines segments from the lethal (TcsL) and hemorrhagic (TcsH) toxins in mice and sheep. Both immunized animal groups exhibited elevated levels of IgG, with the mice demonstrating moderate protection (<50 %) against lethal challenges, comparable to that of the conventional vaccine.

Indole Derivatives as Promising Anti-Dengue Agents: A Review of Recent Advances.

Dengue, a mosquito-borne disease transmitted by Aedes mosquitoes, is a significant global health concern. Despite extensive research, effective treatments remain limited. The indole nucleus, known for its diverse pharmacological properties, has emerged as a promising scaffold for anti-dengue drug discovery.