Publications by authors named "C Cernea"
Article Synopsis
- A global collaborative study reviewed the management and outcomes of malignant skull base tumors, collecting data from 28 institutions involving 3,061 patients.
- The majority of surgeries utilized an open approach (55%), with endoscopic (36%) and combined techniques (9.6%) being less common, and the overall 5-year survival rates were 65% for overall survival (OS) and 71.7% for disease-specific survival (DSS).
- Factors such as older age, comorbidities, and the extent of tumor involvement were identified as independent predictors of survival, while adjuvant radiation therapy (RT) emerged as a protective factor in outcomes.
Head and neck squamous cell carcinoma (HNSCC) is well known as a serious health problem worldwide, especially in low-income countries or those with limited resources, such as most countries in Latin America. International guidelines cannot always be applied to a population from a large region with specific conditions. This study established a Latin American guideline for care of patients with head and neck cancer and presented evidence of HNSCC management considering availability and oncologic benefit.
View Article and Find Full Text PDFIntroduction: The aim of this study is to assess the impact of lymph node ratio (LNR) and number of positive lymph nodes (NPLN) on mortality and recurrence rates in patients with laryngeal squamous cell carcinoma.
Materials And Methods: We conducted a retrospective multicenter international study involving 24 Otorhinolaryngology-Head and Neck Surgery divisions. Disease-specific survival (DSS) and disease-free survival (DFS) were evaluated as the main outcomes.
Objectives: To prospectively compare the results of microvascular flap reconstruction of midface and scalp advanced oncologic defects using superficial temporal versus cervical as recipient vessels.
Methods: This is a parallel group clinical trial with 1:1 allocation ratio of patients who underwent midface and scalp oncologic reconstruction with free tissue flap from April 2018 to April 2022 in a tertiary oncologic center. Two groups were analyzed: those in whom superficial temporal vessels were used as the recipient vessels (Group A) and those in whom cervical vessels were used as the recipient vessels (Group B).