[Evolution of the first hospital pharmacy in Saint-Spiridon hospital of Iasi].

The first Saint-Spiridon hospital was built in 1757. A pharmacy, managed by Andonie Feierman, was opened in 1765. After his death, foreign pharmacists succeeded one another until 1827, when was mentioned the first rumanian pharmacist, Ioan Padure.

[Neurological manifestations on collagenoses].

Collagen diseases are precipitated by very different etiologic factors, but have a common pathogenic mechanism--autoimmune, which evolves chronically and progressively involving new territories. The initial and main pathologic lesions are vascular arterial ischemic (and, according to the prevalently involved territory, the type of disease results: PAN--medium-sized and small arterioles; scleroderma--small arterioles and capillaries), and the secondary ones are the result of ischemia with plurivisceral involvement. Neurological dysfunctions were detected in about 50% of collagen diseases diagnosed during a 25 year interval in the IIIrd Medical Clinic of Iaşi.