The coiled envelope-a disposable insert for coil dialysis.

The coiled envelope, a disposable pre-sterilized insert for coil dialysis, and its associated hardware were developed. In vitro and in vivo characterizations of the dialyzer were carried out and clinical dialyses performed. Clinical studies show the efficacy of the device and indicate advantages in its design.

A biological extracorporeal metabolic device for hepatic support.

The results from OCTOPUS-I indicate that combined metabolic activities could be maintained under the optimal conditions provided for a prolonged period of time, but most effectively up to 14 hrs. The results of OCTOPUS-II and -III are lower than those in OCTOPUS-I. However, the activity in these systems is still higher than those previously reported((18)), which had urea production of 0.